ʻO ka waiwai nui o ka Hydroxyapatite 

Ma ke kahua o nā biomaterials, aia kekahi mea i hoʻopili ʻia i ka hui ʻana o nā iwi a me nā niho kanaka: hydroxyapatite. ʻAʻole kēia mineral kūlohelohe wale nō he mea nui o nā ʻiʻo paʻakikī kanaka akā he hana koʻikoʻi nō hoʻi i ka lāʻau lapaʻau, mālama waha, aesthetics olakino, a me ka ʻepekema biomaterials. I kēia lā, e ʻimi hohonu kākou i kēia mea kupaianaha.

Hydroxyapatite: Hoʻolauna Huahana

ʻO ka Hydroxyapatite kahi mineral calcium phosphate kūlohelohe me ke ʻano kemika Ca₁₀(PO₄)₆(OH)₂, a ʻo ia ka mea nui inorganic o nā iwi vertebrate a me nā niho. I loko o ke kino kanaka, ʻoi aku ka hydroxyapatite ma kahi o 60-70% o ka iwi iwi a ma luna o 90% o ka enamel niho.

Loaʻa i kēia mea kahi ʻano kristal kūʻokoʻa, nona ka ʻōnaehana kristal hexagonal, e hāʻawi iā ia i nā waiwai kino a me nā kemika. ʻAe ka ʻenehana hou i ka synthesis o ka hydroxyapatite ma o nā ʻano like ʻole, me ka hydrothermal synthesis, precipitation, a me nā ʻano sol-gel, e ʻae ai i ka mana pololei ma luna o kona maʻemaʻe, ʻano kristal, a me ka morphology particle e like me nā koi noi like ʻole.

Mechanism o ka hana: Biocompatibility a me ka bioactivity

Mahalo nui ʻia ka Hydroxyapatite ma ke kahua biomedical ma muli o ʻelua mau hiʻohiʻona nui:

Biocompatibility: No ka mea ʻo ka hydroxyapatite he ʻāpana o nā iwi a me nā niho o ke kanaka, he pili maoli kona me nā ʻiʻo kanaka a ʻaʻole ia e hōʻole a i ʻole nā ​​mea ʻawaʻawa.

Bioactivity: Ke hoʻopili ʻia ka hydroxyapatite me ka ʻiʻo ola, hiki mai ke ʻano o ka hopena ma ka ʻaoʻao o ka ʻili kino, hana i nā paʻa kemika a hāpai i ka ulu ʻana o ka ʻiʻo iwi hou ma luna o kona ʻili. Ke alakaʻi nei kēia waiwai osteoconductive i nā pūnaewele iwi e neʻe, hoʻopili, a hoʻonui i kona ʻili.

Ma ka pae mole, pili ka hydroxyapatite me nā ʻiʻo a puni ma o ka hoʻololi ion. Hiki i ka calcium a me ka phosphate ions ma luna o kona ʻili ke hoʻololi me nā biomolecules i loko o nā wai o ke kino, e hāpai ana i ka adsorption protein a me ka hoʻopili ʻana i nā cell, a laila e hoʻomaka i ke kaʻina hana hoʻoponopono.

Nā hana he nui: mai ka lāʻau lapaʻau i ka mālama ʻana i kēlā me kēia lā

Loaʻa i ka Hydroxyapatite ka nui o nā noi, ʻoi loa ma nā wahi aʻe:

Nā noi orthopedic: Ma ke ʻano he mea hoʻoponopono iwi, hoʻohana ʻia ia e hoʻopiha i nā hemahema o ka iwi i hoʻokumu ʻia e ka ʻeha, ka ʻoki ʻana i ke koko, a i ʻole nā ​​maʻi hānau; ma ke ʻano he mea kālai iwi, ua hui pū ʻia me nā polymers e hana i nā papa iwi biodegradable, nā iwi iwi, a me nā mea hoʻoponopono kūloko.

Kahua niho: Hoʻohana ʻia no ke kūkulu hou ʻana i ke kuamoʻo alveolar, ka hoʻopiha ʻana i ke kumu niho, a me ka hoʻoponopono ʻana i ka iwi periodontal; ma ke ʻano he toothpaste additive, hiki iā ia ke hoʻomaʻamaʻa i ka enamel niho, hoʻoponopono i nā caries mua, a hoʻemi pono i ka naʻau niho.

Nā ʻōnaehana lawe lāʻau: Ma muli o kona ʻano porous a me nā waiwai adsorption, hiki ke hoʻohana ʻia ma ke ʻano he lawe lāʻau lapaʻau e hoʻokō ai i ka hoʻokuʻu ʻana i ka lāʻau lapaʻau.

ʻO ka lāʻau lapaʻau: Ma ke ʻano he mea hoʻopiha ʻiʻo palupalu, hoʻohana ʻia ia no ka hoʻopiha ʻana i ka helehelena a me ka hoʻopiha ʻana i ka wrinkle, e hāʻawi ana i kahi koho palekana a lōʻihi hoʻi i nā mea hoʻopiha kuʻuna.

ʻO ka Hydroxyapatite, ma ke ʻano he mea biocompatible loa, ke kōkua nei i nā kānaka he nui e kūkulu hou i nā iwi ikaika, nā niho, a me nā ʻiʻo olakino. ʻO ka noi ʻepekema o kēia mineral kūlohelohe e hōʻike maikaʻi loa i ka hui like ʻana o ke ʻano a me ka ʻenehana, a kuhikuhi pū i ke ala no ka hoʻomohala ʻana o nā biomaterials.