Dab tsi yog PDRN? Vim li cas nws thiaj hu ua "tus yuam sij rau cov tshuaj kho dua tshiab"? 

Hauv kev kho tawv nqaij thiab tshuaj kho kom zoo nkauj, "rov tsim dua tshiab" yog lub tswv yim ntxim nyiam. Thaum cov tawv nqaij puas lawm los yog hnub nyoog, peb ib txwm cia siab tias yuav tsa nws lub peev xwm kho lub ntuj. PDRN yog qhov tseeb ntawm "tus yuam sij" uas cov zej zog tshawb fawb tau tshawb pom tsis ntev los no los ua kom cov txheej txheem kho cellular. Hnub no, peb yuav nthuav tawm nws qhov tsis meej.

Keeb kwm: Kev tshoov siab los ntawm lub zog rov qab los ntawm dej hiav txwv

PDRN (Polydeoxyribonucleotide), uas nws lub npe tag nrho yog polydeoxyribonucleotide, tsis yog cov khoom siv tshuaj lom neeg, tab sis yog muab los ntawm cov qog nqaij hlav hauv lub cev.

Cov kws tshawb fawb pom tau tias cov ntses salmon muaj cov ntaub so ntswg muaj zog thiab kho lub peev xwm. Los ntawm kev tshawb fawb ntxiv, lawv tau rho tawm cov DNA tshwj xeeb-PDRN-los ntawm cov phev ntses ntses. Cov DNA no zoo sib xws hauv cov qauv tseem ceeb rau DNA ntawm tag nrho cov tsiaj txhu (xws li tib neeg), ua kom pom cov biocompatibility zoo heev thiab tsis tshua muaj kev pheej hmoo ntawm kev tiv thaiv kab mob, yog li tso cai rau nws muaj kev nyab xeeb thiab siv tau zoo hauv tib neeg lub cev.

Qhov tseem ceeb: Nws tsis yog tsuas yog "cov khoom siv raw," tab sis kuj yog "cim".

Peb tuaj yeem nkag siab txog cov txheej txheem ntawm kev ua ntawm PDRN los ntawm ob lub ntsiab lus tseem ceeb:

Raws li "cov khoom kho": PDRN yog tsim los ntawm ntau cov deoxyribonucleotides (cov ntsiab lus ntawm DNA). Thaum cov ntaub so ntswg puas lawm thiab cov hlwb yuav tsum tau faib thiab loj hlob los kho kom tiav, cov nucleotides uas muaj tam sim no tuaj yeem siv ncaj qha los ntawm cov hlwb los ua cov khoom siv raw rau kev sib txuas DNA tshiab, yog li ua kom cov txheej txheem kho dua.

Raws li "kho teeb liab": Qhov no yog qhov tseem ceeb thiab tshwj xeeb ntawm kev ua ntawm PDRN. PDRN tuaj yeem raug lees paub tshwj xeeb los ntawm cov hlwb nyob ib puag ncig cov ntaub so ntswg puas lossis hypoxic thiab khi rau adenosine A2A receptors ntawm lub xovtooj ntawm tes, inhibiting NF-kB thiab MAPK signaling pathways qhib los ntawm ROS.  Qhov no txo ​​qis kev tsim cov pro-inflammatory cytokines (IL-6, IL-1β, TNF-α, thiab lwm yam) thiab txhawb kev qhia ntawm cov tshuaj tiv thaiv cytokines (IL-10), yog li ua rau muaj zog tiv thaiv kab mob.  Tsis tas li ntawd, nws txhawb kev tso tawm ntawm EGF (kev loj hlob ntawm epidermal), FGF (fibroblast kev loj hlob zoo), VEGF (vascular endothelial txoj kev loj hlob), thiab angiopoietin, muab PDRN zoo heev los tiv thaiv kab mob thiab qhov txhab zoo.

Core muaj nuj nqi: Kev kho cov saw hlau los ntawm micro mus rau qib macro.

Raws li cov txheej txheem tau piav qhia saum toj no, PDRN siv cov kev cuam tshuam zoo ntawm cov tawv nqaij:

Txhawb nqa angiogenesis: Ua kom cov ntshav txaus rau qhov chaw puas, nqa cov pa oxygen thiab cov as-ham thiab tshem tawm cov khoom pov tseg hauv metabolic.

Txhawb nqa cell proliferation thiab migration: Accelerates cov dej num thiab cov xov tooj ntawm cov tseem ceeb kho hlwb xws li fibroblasts thiab keratinocytes.

Stimulates collagen thiab elastin synthesis: Strengthes daim tawv nqaij qauv ntawm lub dermis, txhim kho cov kab zoo thiab nce elasticity.

Hwj chim los tiv thaiv cov nyhuv: Zoo soothes inflammatory kev tshwm sim xws li liab, o, kub, thiab mob los ntawm regulating inflammatory yam.

Kev kho cov ntaub so ntswg thiab qhov txhab zoo:  Combining tag nrho cov teebmeem saum toj no, nws ua kom cov txheej txheem kho mob ntawm ntau yam tawv nqaij raug mob.

PDRN yog hu ua "tus yuam sij rau kev tsim dua tshiab" vim tias nws tsis tsuas yog kho thiab txhawb nqa, tab sis tswj hwm kev ua haujlwm ntawm tes.  Raws li nws cov biocompatibility siab, nws activates daim tawv nqaij tus kheej regenerative muaj peev xwm los ntawm ntau txoj kev synergistic teebmeem. Qhov txheej txheem ntawm "ua kom muaj peev xwm kho qhov muaj peev xwm" yog qhov tseem ceeb hauv kev tsim kho dua tshiab, thiab nws yog qhov ua rau PDRN nws txoj haujlwm tsis tuaj yeem hloov pauv hauv kev noj qab haus huv ntawm daim tawv nqaij.