Daily-use 45S5 Bioactive Glass
45S5 Bioactive Glass is a clinically proven bioactive material known for excellent bone regeneration, osteoconductivity, and biocompatibility. It stimulates hydroxyapatite formation and is widely used in bone repair, dental, and medical applications.
Description
marker
45S5 Bioactive Glass Product Description
Bioactive glass is a novel type of biomaterial used for tissue regeneration, possessing biological activity, compatibility with both soft and hard tissues, and controllable degradation rates.
The most representative bioactive glass used clinically for bone, tooth, and skin wound repair is 45S5, which belongs to the Na2O-CaO-SiO2-P2O5 quaternary system.
This novel medical material exhibits excellent biocompatibility and, in a physiological environment, can generate a bone-promoting hydroxycarbonate apatite mineralization layer through mineralization deposition on its surface, thereby achieving chemical bonding between the material and the host tissue.
45S5 Bioactive Glass Product Specification
| Raw Material Name | Daily-use 45S5 Bioactive Glass |
| Function | Anti-inflammatory, antibacterial, barrier repair |
| Rinse-off Product Addition Level | 1%-30% |
| Leave-on Product Addition Level | 0.1%-5% |
| Specification | 100g/500g/1kg |
| Lead Time | CN202610037550.3 |
| Patent Information | CN202610272536.1 CN202610742561.1 |
| Technical Documentation Package | Cosmetic Raw Material Safety Information Registration with the National Medical Products Administration + Safety Information (Appendix 14) + Inventory of Used Cosmetic Ingredients + COA (Chinese/English) + MSDS (Chinese/English) |
45S5 Bioactive Glass Functional Role
I.Promoting Bone Bonding
The implant surface can form strong chemical bonds directly with bone tissue.
This is not merely physical adhesion, but the formation of a hydroxyapatite (HCA) layer similar to natural bone
II.Promoting Osteogenesis and Bone Regeneration
●Release of ions such as Ca²⁺, SiO₄⁴⁻, PO₄³⁻, and Na⁺
●Stimulation of osteoblasts:
o Increased cell proliferation
o Promotion of osteogenesis-related gene expression
o Accelerated new bone formation
III. Induction of Hydroxycarbonate Apatite (HCA) Layer Formation
The following classic reaction process occurs in body fluids:
1.Na⁺ exchanges with H⁺, creating an alkaline environment.
2.The Si-O-Si network breaks down, forming Si-OH.
3.Ca²⁺ and PO₄³⁻ accumulate on the surface.
4.An HCA layer is formed (similar to natural bone mineral).
IV.Antibacterial and Infection Inhibition
●Ion release increases local pH and osmotic pressure.
●Inhibits the growth of various bacteria.
●Can reduce the risk of postoperative infection.
V.Controlled Degradation and Tissue Replacement
●The material gradually degrades in the body.
●Simultaneously, it is replaced by newly formed bone tissue.
●The degradation rate can be controlled through the composition ratio and particle size.
45S5 Bioactive Glass Usage Format
1.Orthopedics / Bone Defect Repair: Direct implantation of granules or powder into the defect; or used to create bone scaffolds.
2.Dentistry: Powder added to toothpaste, dental patches, and periodontal filling materials.
3.Wound Repair / Soft Tissue Engineering: Combined with hydrogels, dressings, or membranes, in micro/nanoparticle form.
4.Cosmetics / Anti-aging Repair (R&D stage): Micro-powder added to face masks or cosmetic materials.
5.Antibacterial Materials: Combined with hydrogels, dressings, or coatings.
contact us
Related popular products
(DK Type)Medical Microsphere Hydroxyapatite
Dental desensitizers, hemostatic materials, wound dressing materials Rapid-effect superficial subcutaneous injection Rapid-effect medical aesthetic filler (deep subcutaneous and supraperiosteal injection)
(SOD-bio-2k) Medical Superoxide Dismutase
Recombinant Human Superoxide Dismutase with enzyme activity ≥10000 U/mg, purity ≥95%, stable dimer structure and molecular weight of 32 kDa.
Medical Nano Hydroxyapatite
Bone repair materials, injectable bone fillers, bioactive coatings for metal implants, hemostatic material 3D-printed scaffolds, antibacterial metal-loaded composite scaffolds, tooth desensitizers, dental composite resin fillers, dental implant coatings, tooth root implantation, dental defect filling, drug and gene delivery carriers, maxillofacial surgical repair membranes, wound dressings
Daily-use Recombinant Human Superoxide Dismutase
Recombinant Human Superoxide Dismutase with enzyme activity ≥10000 U/mg, purity ≥95%, stable dimer structure and molecular weight of 32 kDa.
Polydeoxyribonucleotide
PDRN (polydeoxynucleotide) is a DNA fragment extracted from salmon cells. It shares approximately 98% homology with human DNA. Self-produced PDRN has a molecular weight ≤100 bp and provides nucleic acid bases during cellular metabolism.
Soothing Facial Mask
This soothing sheet mask features patented sodium hyaluronate, panthenol, hydroxyapatite, and fermented botanical extracts to help hydrate, calm, and support the skin barrier. Designed for sensitive skin, it delivers comfortable care with a soft, skin-friendly microfiber sheet.
HairG Hair Serum
HairG Hair Growth Serum features PDRN and targeted hair-growth peptides to support scalp balance and hair vitality. It helps soothe and nourish the scalp, improve the scalp environment, strengthen the scalp barrier, and support healthier, thicker-looking hair. The minimalist, additive-free formula contains no hormones, preservatives, or harsh ingredients, making it gentle and suitable for sensitive scalps.
Rose PDRN
PDRN (polydeoxynucleotide) is a DNA fragment extracted from salmon cells. It shares approximately 98% homology with human DNA. Self-produced PDRN has a molecular weight ≤100 bp and provides nucleic acid bases during cellular metabolism.
Daily-use Hydroxyapatite
Bone repair materials, injectable bone fillers, bioactive coatings for metal implants, hemostatic material 3D-printed scaffolds, antibacterial metal-loaded composite scaffolds, tooth desensitizers, dental composite resin fillers, dental implant coatings, tooth root implantation, dental defect filling, drug and gene delivery carriers, maxillofacial surgical repair membranes, wound dressings
(SDK Type)Medical Microsphere Hydroxyapatite
Bioactive coating for implant surfaces, bone repair materials Long-lasting superficial subcutaneous injection Long-lasting regenerative medical aesthetic filler (deep subcutaneous and supraperiosteal injection)
(SOD-1W) Medical Superoxide Dismutase
Recombinant Human Superoxide Dismutase with enzyme activity ≥10000 U/mg, purity ≥95%, stable dimer structure and molecular weight of 32 kDa.
Liquid Dressing
Medical-grade recombinant collagen and hyaluronic acid blend designed for advanced tissue repair and skin regeneration. Enhances hydration, supports wound healing, and improves skin elasticity. Ideal for medical, aesthetic, and biomedical applications.
Medical 45S5 Bioactive Glass
Medical 45S5 Bioactive Glass is a clinically proven bioactive material known for excellent bone regeneration, osteoconductivity, and biocompatibility. It stimulates hydroxyapatite formation and is widely used in bone repair, dental, and medical applications.
(HD Type) Medical Microsphere Hydroxyapatite
Local drug/active ingredient sustained-release carriers, drug-loaded coatings Drug-loaded sustained-release carriers Active-guided bone regeneration microspheres, balanced tissue-integration medical aesthetic fillers, hemostatic microspheres
Reparied Cream
This face cream is formulated with salmon-derived PDRN, combined with SOD, niacinamide, squalane, pro-xylane, panthenol, and peptides. It helps maintain skin hydration, comfort, and a healthy-looking appearance while supporting the skin’s natural barrier. The lightweight texture absorbs easily without greasiness, making it suitable for daily use. Free from alcohol, hormones, and heavy metals, it is designed for regular skincare routines and can also be applied as a mask for extra nourishment.
(SOD-bio-5k) Medical Superoxide Dismutase
Recombinant Human Superoxide Dismutase with enzyme activity ≥10000 U/mg, purity ≥95%, stable dimer structure and molecular weight of 32 kDa.
Please leave us a message.