I-Hydroxyapatite Ca/P Retio: Kutheni ibalulekile kuZinyo kunye neMathiriyeli yokuLungisa aMathambo 

I-Hydroxyapatite yenye yezona zinto zibalulekileyo ze-calcium phosphate ezisetyenziswa kumazinyo, ukunakekelwa komlomo, ukulungiswa kwamathambo kunye nezicelo ze-biomedical. Kubaqulunqi, abavelisi bezinto zamazinyo kunye nabaphuhlisi be-biomaterial, enye iparameter yobugcisa ifanelwe ingqalelo ekhethekileyo: i-hydroxyapatite Ca / P ratio.

Umlinganiselo we-Ca/P ubhekisela kumlinganiselo we-molar phakathi kwe-calcium kunye ne-phosphorus kwi-hydroxyapatite okanye ezinye izinto ze-calcium phosphate. Kwi-stoichiometric hydroxyapatite, umlinganiselo ofanelekileyo weCa / P udlalwa ngokuqhelekileyo njenge-1.67. Eli xabiso ayililo nje inani lethiyori. Inxulumene ngokusondeleyo nokubunjwa kwesigaba, ukuzinza, ukunyibilika, ukusebenza kwezinto eziphilayo kunye nokusetyenziswa kokugqibela kwezinto.

Kwiinkampani ezifumana i-hydroxyapatite powder, ukuqonda umlinganiselo we-Ca / P kunceda ukuvavanya ukuba izinto eziphathekayo zifanelekile kwi-toothpaste, iimveliso ze-enamel remineralization, izinto zamazinyo, ukufakwa kweengubo zokufakelwa, i-bone graft substitutes okanye ezinye iinkqubo eziphambili ze-biomaterial.

Yintoni na Ca/P Umlinganiselo kwiHydroxyapatite?

I-Hydroxyapatite ine-chemical formula Ca10 (PO4) 6 (OH)2. Ngokusekelwe kule fomyula, umlinganiselo we-molar we-calcium kwi-phosphorus ngu-10: 6, odla ngokuba lula njenge-1.67.

Yingakho i-1.67 ihlala ithathwa njengereferensi yeCa / P ye-stoichiometric hydroxyapatite.

Nangona kunjalo, ayizizo zonke iipowders ze-hydroxyapatite zi-stoichiometric ngqo. Ngokuxhomekeke kwizinto eziluhlaza, indlela yokudibanisa, ubushushu bokucubungula kunye neemeko emva kokunyanga, i-hydroxyapatite ingabonisa ukuhluka okuncinci kwi-Ca / P ratio. Ezi zintlukwano zinokuchaphazela iipropati zezinto zokugqibela.

Umlinganiselo we-Ca / P osondeleyo kwi-1.67 ngokuqhelekileyo ubonisa isigaba esicebileyo se-hydroxyapatite. Umlinganiselo ophantsi unokucebisa i-calcium-deficient hydroxyapatite okanye ubukho bezinye izigaba ze-calcium phosphate. Umlinganiselo ohluke kakhulu unokubonisa ukuba izinto zifuna uhlalutyo lokuqulunqwa kwesigaba esongezelelweyo ngaphambi kokusetyenziswa kwiimveliso zamazinyo okanye ze-biomedical.

Kutheni i-Hydroxyapatite Ca/P Retio ibalulekile

Umlinganiselo weCa/P ubalulekile kuba unceda ukuchaza ukulingana kwemichiza kunye neempawu zesigaba semathiriyeli ye-calcium phosphate. Kwizicelo zokulungiswa kwamazinyo kunye namathambo, le bhalansi inokuchaphazela izinto ezininzi eziphambili zokusebenza.

1. Ukuqulunqwa kweSigaba

IHydroxyapatite lilungu elinye kuphela lentsapho ye-calcium phosphate. Ezinye izinto ze-calcium phosphate, ezifana ne-tricalcium phosphate, i-dicalcium phosphate kunye ne-amorphous calcium phosphate, zinemilinganiselo eyahlukeneyo ye-Ca / P kunye neempawu ezahlukeneyo.

Umzekelo, i-tricalcium phosphate ngokubanzi ine-Ca/P ratio esezantsi kune-hydroxyapatite. Iqhele ukunyibilika ngakumbi kwaye iphinda ihlaziye ngokukhawuleza kwindawo yebhayoloji. IHydroxyapatite, ngokuthelekisa, ihlala izinzile kwaye ayinyibiliki kangako.

Yiyo loo nto uhlalutyo lwe-Ca/P luluncedo ngexesha lovavanyo lwempahla ekrwada. Inceda ukuchonga ukuba i-powder iyinhloko ye-hydroxyapatite okanye ingaba iqulethe ezinye izigaba ze-calcium phosphate.

2. Ukunyibilika kunye nokuzinza

Umlinganiselo weCa/P unokuphembelela indlela imathiriyeli yecalcium phosphate eziphatha ngayo kwindawo enamanzi okanye yebhayoloji.

Kwizicelo zokunakekelwa komlomo, ezifana ne-toothpaste kunye ne-formulation yokuhlamba umlomo, ukusebenzisana kwamaminerali okulawulwayo kubalulekile. I-hydroxyapatite powder kunye ne-balance balance yamakhemikhali inokuxhasa i-enamel-focusing formulations, ngelixa iphinda igcine ukuhambelana kakuhle kunye nayo yonke ifomyula.

Kwizinto zokulungisa amathambo, ukunyibilika kunye nokuziphatha kwe-resorption kubaluleke ngakumbi. Isixhobo esinyibilika ngokukhawuleza sisenokunganikeli nkxaso yaneleyo yesakhiwo. Izinto ezizinzile kakhulu zinokuhlala ixesha elide kwaye zidibanise ngokuhlukileyo kunye nokwakhiwa kwamathambo amatsha. Umlinganiselo weCa/P awumiselanga ntsebenzo yodwa, kodwa sesinye sezalathisi ezisisiseko ezisetyenziselwa ukuqonda indlela yokuziphatha kwezinto.

3. Ukufana kweBiological kwiiTissues ezinzima

I-Hydroxyapatite ifundwa ngokubanzi kuba ifana neekhemikhali kwisigaba samaminerali samazinyo kunye nethambo lomntu. Oku kufana sesinye isizathu sokuba i-hydroxyapatite isetyenziswe kwizinto zamazinyo, ukufakwa kweengubo zokufakelwa kunye neemveliso zokulungisa amathambo.

Ukusetyenziswa kwamazinyo, i-hydroxyapatite ixabiswa ngenxa yokuba i-enamel yezinyo kunye ne-dentin zizicubu ezityebileyo ngamaminerali. Ekuqulunqweni kokunakekelwa komlomo, i-nano okanye i-micro hydroxyapatite ingasetyenziselwa njengento esebenzayo yamaminerali kwiimveliso ezinxulumene ne-enamel.

Ukusetyenziswa kokulungiswa kwamathambo, i-hydroxyapatite isetyenziswe ngenxa ye-biocompatibility yayo, i-osteoconductive ikhono kunye nokufana ne-mineral bone mineral. Umlinganiselo ofanelekileyo weCa / P unceda ukuqinisekisa ukuba izinto eziphathekayo zigcina iimpawu ezilindelekileyo ze-hydroxyapatite.

4. Ukulawulwa koMgangatho kubathengi beMathiriyeli ekrwada

Kubathengi be-B2B, umlinganiselo we-Ca / P yipharamitha yokulawula umgangatho osebenzayo. Xa kuthengwa i-hydroxyapatite powder, iinkampani akufanele zicele kuphela ubukhulu be-particle kunye nobunyulu. Kufuneka kwakhona bahlaziye ukubunjwa kweekhemikhali, umlinganiselo we-Ca / P, ukucoceka kwesigaba kunye nemida yentsimbi enzima.

Umniki-nkonzo othembekileyo kufuneka akwazi ukubonelela ngeSatifikethi sokuHlalutya, iphepha ledatha yobugcisa kunye nolwazi lokuvavanya. Kuphuhliso lwamazinyo okanye lwebhayoloji, amaxwebhu ongezelelweyo anokufuneka ngokuxhomekeke kwimarike ekujoliswe kuyo kunye nendlela yolawulo.

Umlinganiselo weCa/P ofanelekileyo: Ngaba i-1.67 isoloko iyeyona ilungileyo?

Umlinganiselo we-Ca / P we-1.67 ngokuqhelekileyo uthathwa njengexabiso elifanelekileyo le-stoichiometric hydroxyapatite. Nangona kunjalo, "efanelekileyo" kuxhomekeke kwisicelo.

Kwizicelo ezifuna i-hydroxyapatite ezinzileyo kunye nokuhlanjululwa kwesigaba esiphezulu, umlinganiselo we-Ca / P osondeleyo kwi-1.67 ukhethwa ngokubanzi. Oku kunokubandakanya imathiriyeli yamazinyo, imathiriyeli yokufaka ukutyabeka ekrwada kunye neenkqubo ezithile zokulungisa amathambo.

Ukusetyenziswa apho ukutshintshwa ngokukhawuleza okanye ukuthotywa okulawulwayo kufunwa, izixhobo ezinezigaba ezahlukeneyo ze-calcium phosphate zinokukhethwa. Ngokomzekelo, izinto ze-biphasic calcium phosphate zihlala zidibanisa i-hydroxyapatite kunye ne-tricalcium phosphate ukulinganisela ukuzinza kunye ne-resorption.

Ngoko ke, abathengi akufanele bajonge umlinganiselo weCa/P kuphela. Kufuneka ihlolwe kunye nokubunjwa kwesigaba, i-crystallinity, ubukhulu be-particle size, i-morphology, indawo ephezulu kunye nesicelo esijoliswe kuyo.

I-Hydroxyapatite Ca/P Umlinganiselo kwi Izinto zamazinyo

Ukusetyenziswa kwamazinyo kufuna ukulawulwa ngokucophelela komgangatho wezinto eziphathekayo kuba isithako sinokusebenzisana ne-enamel, i-dentin, i-saliva kunye nezinye izinto zokuqulunqa.

I-Hydroxyapatite powder ingasetyenziswa kwiimveliso ezininzi ezinxulumene namazinyo, kubandakanya:

• I-toothpaste kunye ne-oral care formulations
• Iimveliso zamazinyo ezibangela ubuthathaka
• Iimveliso ze-enamel remineralization
• Izinto zokuthambisa zamazinyo
• Iimbumba zamazinyo
• Imathiriyeli yonyango lomphezulu wokufakelwa
• Iingubo ze-Hydroxyapatite zokufakelwa kwamazinyo

Kwiimveliso ze-toothpaste kunye nokunakekelwa komlomo, i-nano hydroxyapatite isoloko ikhethwa ngenxa yokuba iincinci ezincinci zingahlakazeka ngokulula kwaye zidibanise ngokusondeleyo kunye neendawo zamazinyo. Nangona kunjalo, ubungakanani bamasuntswana bubodwa abanelanga. Umlinganiselo weCa / P kunye nokubunjwa kwesigaba kubaluleke kakhulu kuba kunceda ukufumanisa ukuba i powder ihambelana ngokwenene neempawu ze-hydroxyapatite.

Kwizinto zokufakelwa kwamazinyo kunye nezixhobo zamazinyo eziphambili, ukuhambelana kweekhemikhali kubaluleke ngakumbi. Abavelisi bafuna i-hydroxyapatite powders enobunyulu obuthembekileyo, umgangatho ozinzileyo webhetshi kunye namaxwebhu afanelekileyo obugcisa.

I-Hydroxyapatite Ca / P Umlinganiselo kwizinto zokuLungisa amathambo

I-Hydroxyapatite isetyenziselwa ngokubanzi ukulungiswa kwamathambo kunye nophando lwe-orthopedic biomaterial. Ukufana kwayo kweekhemikhali kwiminerali yethambo kuyenza ilungele izicelo ezinje:

• Imathiriyeli yethambo yokufakela indawo
• Izizalisi ezingenanto zamathambo
• Izikafu zeBioceramic
• Iingubo ze-Hydroxyapatite kwi-metallic implants
• Izinto ezidibeneyo kunye ne-collagen, iipolymers okanye i-β-TCP
• I-3D eprintiweyo yokulungisa i-scaffolds yamathambo

Kwezi zicelo, umlinganiselo weCa / P unceda abaphuhlisi ukuba baqonde ukuba izinto eziphathekayo zisondele kwi-stoichiometric hydroxyapatite, i-calcium-deficient hydroxyapatite okanye esinye isigaba se-calcium phosphate.

Kwizinto zokulungisa amathambo, ibhalansi phakathi kokuzinza kunye ne-resorption ibalulekile. I-Hydroxyapatite idla ngokuzinza ngakumbi, ngelixa i-tricalcium phosphate ithande ukubuyiswa ngokukhawuleza. Abanye abaphuhlisi be-biomaterial basebenzisa i-biphasic calcium phosphate ukudibanisa iingenelo zazo zombini izixhobo.

Oku kuthetha ukuba umlinganiselo weCa/P ekujoliswe kuwo kufuneka uhambelane noyilo lwemveliso. Isixhobo esicocekileyo se-hydroxyapatite sinokufaneleka xa uzinzo lwexesha elide kunye nenkxaso ye-osteoconductive ifunwa. I-composite okanye i-biphasic material inokuthi ifaneleke ngakumbi xa i-resorption elawulwayo iyinxalenye yesicwangciso soyilo.

Ca/P Umlinganiselo kunye neSigaba soBunyulu

Umlinganiselo weCa/P okufutshane ne-1.67 luphawu oluluncedo, kodwa alubonakalisi ubunyulu besigaba ngokwaso. Izixhobo ezibini zinokuba nemilinganiselo efanayo yeCa/P kodwa ukuqanjwa kwezigaba ezahlukeneyo, ubukristale okanye ukungcola.

Yiyo loo nto ulawulo lobungcali lwe-hydroxyapatite luhlala lubandakanya iimvavanyo ezininzi, ezinje:

• Uhlalutyo lomxholo we-calcium kunye ne-phosphorus
• Ca/P imolar ratio yokubala
• I-X-ray diffraction yokuchongwa kwesigaba
• Uhlalutyo lwe-FTIR lwamaqela asebenzayo
• Ukuhanjiswa kobungakanani besuntswana
• Uhlalutyo lwe-SEM lwe-morphology
• Uvavanyo lwentsimbi enzima
• Ilahleko ekomisweni
• Uvavanyo lweMicrobial, ukuba lufunwa sisicelo

Kubathengi bamazinyo kunye ne-biomedical, ukucela kuphela "ukucoceka okuphezulu kwe-hydroxyapatite" akwanele. Indlela yobuchwephesha ngakumbi kukucela iinkcukacha ezicacileyo kunye nokuqinisekisa ukuba izinto eziphathekayo ziyahambelana nokusetyenziswa okucetywayo.

Ichaphazela njani iNdlela yoQhagamshelwano yeCa/P

I-Hydroxyapatite powder inokuveliswa ngeendlela ezahlukeneyo, kubandakanywa imvula emanzi, i-hydrothermal synthesis, i-sol-gel processing kunye ne-solid-state reactions. Indlela nganye inokuchaphazela umlinganiselo wokugqibela we-Ca / P, isakhiwo sekristale, ubungakanani be-particle kunye ne-morphology.

Ngokomzekelo, imvula emanzi isetyenziswa ngokuqhelekileyo kwimveliso ye-nano okanye i-micro hydroxyapatite. Iimeko zokusabela, i-pH, ubushushu, umthombo we-calcium, umthombo we-phosphate kunye nexesha lokuguga kunokuchaphazela ukubunjwa kokugqibela.

I-Hydrothermal synthesis inokuvelisa ii powders ezinekristale ephezulu kunye ne-morphology elawulwayo. Iindlela zombuso oqinileyo zingasetyenziselwa izixhobo ze-ceramic-grade kodwa zihlala zifuna amaqondo obushushu aphezulu.

Ngenxa yolu mahluko, iipowder ezimbini ze-hydroxyapatite ezinomlinganiselo ofanayo we-particle ogama zingenza ngokuhlukileyo kwifomula okanye inkqubo ye-biomaterial. Yingakho abathengi kufuneka bavavanye zombini idatha yeekhemikhali kunye nokusebenza kwesicelo.

Indlela yokukhetha i-Hydroxyapatite Powder esekelwe kwi-Ca / P Ratio

Xa ukhetha i-hydroxyapatite powder, umlinganiselo we-Ca / P kufuneka uthathwe njengenxalenye yovavanyo olupheleleyo lobugcisa.

NgeeNkekelo zoLondolozo loMlomo

Kwintlama yamazinyo, i-mouthwash kunye ne-enamel-focused formulations, abathengi kufuneka baqwalasele:

• Umlinganiselo we-Ca / P usondele kwiimpawu ze-hydroxyapatite
• Ubungakanani obufanelekileyo be-particle, njenge-nano okanye i-fine micro powder
• I-dispersibility enhle kwifomula
• Umxholo wentsimbi enzima ephantsi
• Umgangatho ozinzileyo webhetshi ukuya kwibhetshi
• Ukuhambelana ne-humectants, i-thickeners kunye ne-surfactants
• Ukufaneleka ngokusemthethweni kwimarike ekujoliswe kuyo

KwiiMathiriyeli zamazinyo

Kwizinto ezidityanisiweyo zamazinyo, imathiriyeli yokugulisa, ukufakwa kwezinto zokufakelwa okanye ukufakwa konyango lomphezulu, abathengi kufuneka bathathele ingqalelo:

• Ukucoceka kwesigaba
• Ca/P umlinganiselo
• Ubukhazikhazi
• Imofoloji yesuntswana
• Ukuzinza kwe-Thermal
• Ukuqukuqela kunye nokuziphatha kokucubungula
• Amaxwebhu ababoneleli kunye nenkqubo yokulawula umgangatho

Kwizinto zokulungisa ithambo

Ukufakelwa kwamathambo, i-scaffolds ye-bioceramic kunye neengubo zokufakelwa, abathengi banokudinga ukuvavanya:

• Umlinganiselo weCa/P kunye nokwakheka kwesigaba
• I-Hydroxyapatite okanye i-biphasic calcium phosphate design
• I-Porosity kunye ne-morphology
• Idatha ye-Biocompatibility
• Ukuhambelana kokuvala inzala
• Landela into kunye nemida yentsimbi enzima
• Imigangatho kunye neemfuno zolawulo kusetyenziso olucetywayo

Ukungaqondani okuqhelekileyo malunga ne-Hydroxyapatite Ca/P Ratio

Ukungaqondi kakuhle 1: Umlinganiselo oPhezulu weCa/P usoloko uthetha uMgangatho ongcono

Umlinganiselo ophezulu weCa/P awuthethi ngokuzenzekelayo ukusebenza ngcono. Umlinganiselo ochanekileyo uxhomekeke kwithagethi ye-calcium phosphate isigaba kunye nokusetyenziswa kwayo.

Kwi-stoichiometric hydroxyapatite, i-1.67 yixabiso eliqhelekileyo lokubhekisela. Ukuba umlinganiselo uphezulu kakhulu okanye uphantsi kakhulu, uhlalutyo olongezelelweyo luyafuneka.

Ukungaqondi kakuhle i-2: I-Ca/P Retio yodwa iqinisekisa ukusebenza kweMveliso

Umlinganiselo weCa/P ubalulekile, kodwa ayisosibonisi somgangatho kuphela. Ubungakanani be-particle, i-morphology, i-crystallinity, indawo engaphezulu, ukungcola kunye nokuhambelana nokuqulunqwa kuchaphazela ukusebenza.

Ukungaqondi kakuhle i-3: Zonke ii-Hydroxyapatite Powders ziyafana

I-Hydroxyapatite powders inokuhluka kakhulu kuxhomekeke kwindlela yokuvelisa kunye nokulawula umgangatho. Ipowder eyenzelwe ukunakekelwa komlomo ayinakufanelana nokufakwa kweengubo zokufakelwa. Umgubo osetyenziselwa uphando awunakuhlangabezana neemfuno zorhwebo zamazinyo okanye iimveliso zebhayoloji.

Ukungaqondi kakuhle i-4: I-Nano Hydroxyapatite ifuna kuphela ubungakanani beNcinci encinci

Ubungakanani beNano bubalulekile kwizicelo ezithile, kodwa i-nano hydroxyapatite nayo ifuna ukubunjwa kweekhemikhali ezifanelekileyo, ukuhlolwa kokhuseleko, ukuchithwa kunye nokuhambelana kwebhetshi. Ubungakanani obuncinci be-particle ngaphandle kwe-Ca / P ethembekileyo kunye nedatha yokucoceka ayanele kuphuhliso lwemveliso yobuchwephesha.

Zeziphi iiNkcazo ekufuneka aBathengi Bazicele?

Xa ukhangela i-hydroxyapatite powder, abathengi kufuneka bacele iphakheji ecacileyo epheleleyo. Amaxwebhu abalulekileyo asenokuquka:

• Isatifiketi sokuHlalutya
• Iphepha leDatha lobuGcisa
• Iphepha leDatha loKhuseleko
• Idatha yomlinganiselo weCa/P
• Ukuhanjiswa kobungakanani besuntswana
• Ubunyulu kunye nokwakheka kwesigaba
• Uvavanyo lwentsimbi enzima
• Imida yeMicrobiological, ukuba ikhona
• Iimeko zokugcina ezicetyiswayo
• Isikhokelo sesicelo

Kwizinto zokulungisa amazinyo kunye namathambo, kukwaluncedo ukuxoxa ngefomathi yokugqibela yemveliso kunye nomthengisi. Umthengisi othembekileyo we-hydroxyapatite kufuneka akwazi ukucebisa amabakala afanelekileyo ngokusekelwe kwisicelo, ubungakanani beqhekeza, ubunyulu kunye neemfuno zokucubungula.

Kutheni uSebenza noMboneleli weHydroxyapatite oyiNgcali?

I-Hydroxyapatite ayiyona into elula yempahla. Kumazinyo, ukunakekelwa komlomo kunye nezicelo zokulungisa amathambo, abathengi bafuna umgangatho ozinzile kunye nenkxaso yobugcisa.

Umthengisi oqeqeshiweyo unokunceda abathengi bakhethe ibakala elifanelekileyo le-hydroxyapatite esekwe:

• Indawo yosetyenziso
• Ubungakanani besuntswana ekujoliswe kulo
• Ca/P imfuneko yomlinganiselo
• Inqanaba lokucoceka
• Indlela yokuqhuba
• Inkqubo yokuqulunqa
• Iimfuno zamaxwebhu
• Uvavanyo lwesampulu kunye neemfuno zokunyusa umgangatho

Oku kubaluleke kakhulu kwiimveliso kunye nabavelisi abaphuhlisa iimveliso zokunakekelwa komlomo ezisebenzayo, izinto zamazinyo, izinto ezinxulumene nokufakelwa okanye iinkqubo ze-bioceramic.

Ukuqukumbela

Umlinganiselo we-hydroxyapatite Ca / P yenye yezona zibonakaliso ezibalulekileyo zokuvavanya umgangatho we-hydroxyapatite powder. Umlinganiselo we-Ca / P osondeleyo kwi-1.67 udla ngokuhambelana ne-stoichiometric hydroxyapatite, ngelixa i-ratios eyahlukileyo ingabonisa i-calcium-deficient hydroxyapatite okanye ezinye izigaba ze-calcium phosphate.

Kwizinto zamazinyo, umlinganiselo weCa / P unceda ukuqinisekisa ukuhambelana kweekhemikhali kunye nokufaneleka kokusebenza. Kwizinto zokulungisa amathambo, kunceda ukukhokela ukhetho lwe-hydroxyapatite, i-tricalcium phosphate okanye i-biphasic calcium phosphate systems.

Nangona kunjalo, umlinganiselo weCa/P akufunekanga uvavanywe uwedwa. Abathengi abaziingcali kufuneka kwakhona baphonononge ubunyulu besigaba, ubucwebe, ubungakanani bamasuntswana, imorphology, isinyithi esinzima kunye namaxwebhu ababoneleli.

Kubavelisi abaphuhlisa amazinyo, ukunakekelwa komlomo okanye izinto zokulungisa amathambo, ukukhetha i-powder hydroxyapatite efanelekileyo kuyinyathelo elibalulekileyo ekusebenzeni kwemveliso kunye nokulawula umgangatho.

FAQ

Yintoni umlinganiselo ofanelekileyo weCa/P we-hydroxyapatite?

Umlinganiselo ofanelekileyo weCa / P we-stoichiometric hydroxyapatite udlalwa ngokuqhelekileyo njenge-1.67. Oku kuvela kwi-chemical formula Ca10 (PO4)6 (OH)2.

Kutheni umlinganiselo weCa / P ubalulekile kwi-hydroxyapatite powder?

Umlinganiselo weCa / P unceda ukubonisa ukubunjwa kweekhemikhali, iimpawu zesigaba kunye nokuhambelana kwezinto. Yiparameter yomgangatho obalulekileyo wamazinyo, ukunakekelwa komlomo kunye nezicelo zokulungisa amathambo.

Ngaba umlinganiselo weCa/P we-1.67 uhlala ufuneka?

Akunjalo rhoqo. Umlinganiselo osondeleyo kwi-1.67 ukhethwa kwi-stoichiometric hydroxyapatite, kodwa ezinye izinto ze-calcium phosphate zinokuba nemilinganiselo eyahlukileyo ngokuxhomekeke kwisicelo esijoliswe kuyo.

Kwenzeka ntoni ukuba umlinganiselo weCa/P ungaphantsi kwe-1.67?

Umlinganiselo ophantsi weCa / P unokubonisa i-calcium-deficient hydroxyapatite okanye ubukho bezinye izigaba ze-calcium phosphate. Uvavanyo lokwakhiwa kwesigaba esongezelelweyo luyacetyiswa.

Ngaba i-hydroxyapatite ingasetyenziselwa kwizinto zokulungisa amathambo?

Ewe. I-Hydroxyapatite isetyenziswa ngokubanzi kuphando lokulungiswa kwamathambo kunye nophuhliso lwe-biomaterial ngenxa yokufana kwayo ne-mineral bone mineral kunye neempawu zayo ze-osteoconductive.

Yintoni ekufuneka abathengi bayijonge ngaphandle komlinganiselo weCa/P?

Abathengi kufuneka baphinde bahlole ubungakanani beengqungquthela, ukuhlambuluka kwesigaba, i-crystallinity, i-morphology, imida yensimbi enzima, imida ye-microbial, i-COA, i-TDS kunye namaxwebhu okulawula umgangatho womthengisi.