Izinzuzo ze-PDRN: Imiphumela Yangempela Yempilo Yesikhathi Eside Yesikhumba Nezicubu 

Impendulo esheshayo

Izinzuzo ze-PDRN zihlanganisa yonke into kusukela ekuthuthukiseni i-collagen ukuze isikhumba esibushelelezi kuya ekusheshiseni ukuphulukiswa kokulimala kwemisipha. I-PDRN iyinhlanganisela ekhethekile ejovwayo evuselela izinqubo zokulungisa umzimba wakho, enesikhathi esincane sokuphumula kanye nemiphumela engemihle kubantu abaningi. Qhubeka ufunda ukuze uthole yonke imininingwane.

Uhlu Lokuphakathi

1. Isingeniso: Iyini i-PDRN?
2. Izinzuzo Eziphezulu Ezisekelwe Ebufakazini be-PDRN
3. Ukusetshenziswa Okuvamile Kwezokwelapha ze-PDN
4. Okufanele Ukulindele Ngesikhathi Sokwelashwa kwe-PDRN
5. Ukuphepha kanye Nemiphumela Eseceleni Engaba Khona ye-PDRN
6. Imibuzo Evame Ukubuzwa Mayelana ne-PDRN
7. Isiphetho: Ingabe I-PDRN Ikulungele?

Isingeniso: Iyini i-PDRN?

I-PDN imele i-polydeoxyribonucleotide, futhi iyinhlanganisela esuselwe ngokwemvelo, hhayi isidakamizwa noma isigcwalisi sokwenziwa.

Ivelaphi i-PDN?Iningi le-PDRN yezinga lezokwelapha likhishwa kumaseli wesidoda se-salmon — alikho ihlaya, lowo ngumthombo ongaguquki, omsulwa esinawo njengamanje. Icutshungulwa kakhulu ukuze isuse noma yiziphi izinto ezingezwani noma i-DNA yangaphandle, ngakho-ke ukungezwani komzimba kuyivelakancane kakhulu.

Isebenza kanjani i-PDRN emzimbeni?isebenza njengomanyolo wamaseli akho, akunjalo? Kubophezela kuma-receptor factor akhahlela izindlela zokulungisa umzimba wakho zibe igiya eliphezulu.Cabanga ngakho njengokweqa utshani obufile - awugcini nje ngokubeka isoyi elisha (njengokugcwalisa), wondla inhlabathi ukuze utshani bakho bukhule buqine futhi bunempilo. Yilokho okuwumongo wokuthi kungani izinzuzo ze-PDN zingezesikhathi eside, hhayi ezesikhashana.

Eminyakeni yami engu-11 ngisebenza ngomuthi ovuselelayo nowobuhle, ngibone i-PDRN isuka ekwelashweni kwe-niche eyaziwa kancane iye kokuthile iziguli zami eziningi eziyicela ngamagama. Kodwa linda, ngiya phambili - ake sihlukanise izinzuzo zangempela ezisekelwe ebufakazini be-PDRN kuqala.

Izinzuzo Eziphezulu Ezisekelwe Ebufakazini be-PDRN

Ake siqale ngezinto ezisekelwa ucwaningo, hhayi nje i-influencer hype. Ucwaningo lwango-2023 oluphuma ku-Journal of Cosmetic Dermatology oluholwa uDkt. Elena Rossi lubheke iziguli ezingama-62 ezithola imijovo ye-PDRN yokuguga kobuso, futhi lwathola ukuthuthuka okubalulekile kuyo yonke imiphumela esiyikhathalelayo. Ake sihlukanise izinzuzo ezintathu eziphezulu ze-PDRN.

1. Ivuselela ukukhiqizwa kwe-collagen ekulweni nokuguga

Lena inzuzo enkulu ye-PDRN yokusebenzisa izimonyo, ngokweqiniso. Uma i-PDRN ijova ku-dermis, ivuselela ama-fibroblasts - amangqamuzana enza i-collagen ne-elastin. Ucwaningo lwe-Rossi lwango-2023 engilushilo lwathola ukwanda okungama-41% kwe-collagen yesikhumba ngemuva kwezinyanga ezi-3 zokwelashwa kwe-PDRN. Lokho kugxuma okukhulu.

Nganginesiguli, uCarla, 52, uthisha webanga lesi-4 waseSeattle, oweza kimi entwasahlobo edlule (April 2023) efuna okuthile okungathuthukisa ukuthungwa kwesikhumba sakhe, hhayi nje ukugcwalisa imigqa ethile. Wenze ukwelapha okungu-3 kwe-PDRN emasontweni angu-8, futhi ngokulandela kwakhe ngo-August, wathi imigqa yakhe emihle eduze kwamehlo akhe yacishe yashabalala, futhi izimonyo zakhe zahamba kahle kakhulu. Lokho kungumlingo wezinzuzo ze-PDRN.

2. Isheshisa ukulungiswa kwezicubu nokuphola kwesilonda

I-PDRN ekuqaleni yenzelwe ukuphulukiswa kwesilonda, hhayi ubuhle, empeleni. Isiza imithambo yegazi emisha ikhule ezicutshini ezilimele, okuletha umoya-mpilo owengeziwe kanye nezakhamzimba endaweni ukusheshisa ukuphulukiswa.Ucwaningo lwango-2022 ku-Journal of Orthopedic and Sports Physical Therapy luthole imijovo ye-PDRN isike isikhathi sokutakula kwezinyembezi ezincane zemisipha cishe ngo-30% uma kuqhathaniswa nokwelashwa okujwayelekile.

Ngibone lesi sandla sokuqala nesinye isiguli, u-Marcus, 28, umgijimi webanga elide osuka eDenver owaklebhula umsipha wenkonyane ekwindla edlule (Septhemba 2022). Wayebheke amasonto angu-12 okululama ngokwelashwa ngokomzimba nje, kodwa wengeza imijovo ye-PDRN, futhi wayesebuyele ekusebenzeni amasonto angamamayela angu-50 kumaviki angu-8 flat.Umehluko omkhulu wesikhathi, akubuzwa.

3. Yehlisa ukuvuvukala futhi ithuthukise ukuthungwa kwesikhumba

I-PDRN ivimba ama-cytokines abangela ukuvuvukala, okungama-molecule amancane abangela ububomvu, ukuvuvukala, kanye nokuthungwa okungalingani kwesikhumba okuningi esikutholayo lapho sikhula. Kuhle kakhulu kubantu abane-rosacea noma izibazi zangemuva kwezinduna, empeleni.

Ima, ake ngabelane ngephutha lomuntu siqu engilenza emuva ngo-2021, ngenkathi ngiqala ukunikeza i-PDRN. Ngacabanga ukuthi izinzuzo ze-PDRN zazingezokuvuselela i-collagen ejulile kuphela, ngakho-ke angizange ngicabange ukuyincoma kumzala wami uLila one-rosacea ebomvu ephikelela ngempela ezihlathini zakhe.Ezinyangeni ezimbalwa kamuva wathola uchungechunge lwezokwelapha ze-PDRN komunye umhlinzeki futhi ububomvu bakhe behla ngo-70%. Ngazikhahlela - ngaphuthelwa ngokuphelele ukuthi enye yezinzuzo ezibalulekile ze-PDRN ukunciphisa ukuvuvukala. Wasifunda kabuhlungu leso sifundo!

Ukusetshenziswa Okuvamile Kwezokwelapha ze-PDN

Njengamanje, ukusetshenziswa okubili okuvame kakhulu kwe-PDN kuhambisana kahle nezinzuzo eziphezulu ze-PDRN esisanda kukhuluma ngazo. Ake sizihlukanise.

1. Izinqubo zokuvuselela isikhumba sezimonyo

Yilokhu abantu abaningi abakufunayo lapho bebuza ngezinzuzo ze-PDRN. Ukusetshenziswa okuvamile kwezimonyo kufaka phakathi: - Ukuvuselelwa kobuso kwekhwalithi yesikhumba iyonke kanye nemigqa emihle - Ukuthuthukisa ukuthungwa kwesibazi sezinduna kanye nokubabomvu kwangemva kokuvuvukala - Ukunciphisa ububomvu obuhlobene ne-rosacea kanye nokuvuvukala - Ukuthuthukisa imiphumela ngemuva kokufakwa kabusha kwe-laser noma ukuxebuka kwamakhemikhali

Empeleni ngiqale ukuzitholela ukwelashwa kwe-PDRN ngokwami ngonyaka odlule, ngemuva kokuthi ukuhlolwa kwami kwesikhumba kwaminyaka yonke kubonise ukulimala kwelanga ekuseni ezihlathini zami. Ngiya kozakwethu e-Portland, ngisebenzisa uhlobo lwe-Rejuran, okuyi-PDRN efundwe kahle kakhulu laphaya. Ngenze ukwelashwa okungu-3 ngamaviki angu-3 ngokuhlukana, futhi ukuthungwa kwesikhumba sami kubushelelezi kakhulu kunezinyanga eziyi-12 ezedlule.Ngaze ngenza nokuhlolwa kwegazi (sihlola izimpawu zokuvuvukala ekusebenzeni kwami ​​​​kwaminyaka yonke) futhi iphrotheni yami ye-C-reactive yehla ukusuka ku-2.1 mg / L kuya ku-1.2 mg / L, ehambisana naleyo nzuzo yokulwa nokuvuvukala ye-PDRN engikhulume ngayo ngaphambili. Kupholile, akunjalo?

2. Ukuvuselelwa kokulimala kwe-musculoskeletal

Lokhu okungakhulunywa kakhulu ngokusetshenziswa, kepha izinzuzo ze-PDRN lapha zihlaba umxhwele, ngokubona kwami. Ngokuvamile isetshenziselwa: - Izinyembezi zemisipha ezincane kuya kwezilinganiselwe - I-Tendinitis (njengendololwane yethenisi noma idolo lomgijimi) - Ukusheshisa ukululama ngemva kokuhlinzwa kwamathambo - Yehlisa ukuvuvukala okungapheli ekulimaleni ngokweqile

Ngikhulume ngoMarcus umgijimi ngaphambili, kodwa ngike ngaba neziguli ezinendololwane yethenisi engapheli ezathola imijovo ye-PDRN futhi zakwazi ukuyeka ukuthatha ama-anti-inflammatories nsuku zonke ngemva kwamasonto angu-6. Lokho kushintsha impilo kubantu abaningi.

Okufanele Ukulindele Ngesikhathi Sokwelashwa kwe-PDRN

Uma ucabanga ngokuzama i-PDRN, cishe uyazibuza ukuthi isipiliyoni sangempela sinjani. Ake ngikuhambise kukho.

1. Inqubo yokwelapha ejwayelekile ye-PDRN

Okokuqala, umhlinzeki wakho uzohlanza indawo yokwelapha futhi ngokuvamile agcobe ukhilimu wokubamba izinombolo imizuzu engu-20-30 ngaphambi komjovo, ukuze uhlale ukhululekile.Ngokwelashwa kobuso, i-PDRN ijovwa njengochungechunge lwemithamo emincane emincane yonke indawo yokwelapha - uhlobo olufana nokwelashwa kwe-mesotherapy. Ukuze uthole imijovo ye-musculoskeletal, ijova ngqo esicutshini esilimele ngokuqondiswa kwe-ultrasound ngokuvamile.

Yonke i-aphoyintimenti, ukusuka ekubambeni kuya ekupheleni, ithatha isikhathi esingaphansi kwehora, ngokuvamile. Akukho ukuhlala ubusuku bonke, akukho i-anesthesia ejwayelekile. Kuyinqubo yasemsebenzini ongayithola ngesikhathi sakho sesidlo sasemini, ngokweqiniso.

2. Imiphumela elindelwe kanye nomugqa wesikhathi wokuthola kabusha

Isikhathi sokuphumula sincane kakhulu ekwelashweni kwe-PDRN, okungenye inzuzo enkulu ye-PDN ethandwa abantu.Ngomjovo wobuso, ungase ube namaqhubu amancane abomvu noma imihuzuko encane izinsuku ezingu-1-2, yilokho kuphela. Abantu abaningi bangabuyela emsebenzini ngosuku olulandelayo ne-concealer encane.

Imiphumela ayenzeki ngokuphazima kweso, nakuba - khumbula, i-PDN ishukumisa umzimba wakho ukuthi wenze izicubu ezintsha, ngakho lokho kuthatha isikhathi. Ngezinzuzo zobuso ze-PDN, uzoqala ukubona ukuthuthuka okucashile emavikini angu-2-3, kube nemiphumela egcwele ngemva kwezinyanga ezingu-3. Ukuze ululame ukulimala, abantu abaningi baqala ukuzwa ubuhlungu obuncane emavikini angu-1-2, ngokuthuthukiswa okugcwele ngaphezu kwamaviki angu-4-6.

Ukuphepha kanye Nemiphumela Eseceleni Engaba Khona ye-PDRN

Manje, asikwazi ukukhuluma ngezinzuzo ze-PDRN ngaphandle kokwethembeka mayelana nokuphepha, akunjalo? Lokho akuxoxiswana nami.

1. Imiphumela emnene evamile ongayilindela

Cishe yonke imiphumela emibi ye-PDRN imnene futhi iyahamba yodwa ezinsukwini ezimbalwa. Kubandakanya: - Ububomvu besikhashana ezindaweni zokujova - Ukulimaza okuncane noma ukuvuvukala - Ukuluma okuncane noma ukuzwela usuku noma ezimbili

Imiphumela emibi kakhulu efana nokutheleleka noma ukungezwani komzimba ayivamile kakhulu - ngaphansi kuka-0.1% weziguli ocwaningweni lwe-Rossi lwango-2023 zaba nanoma yiluphi uhlobo lokusabela oludinga ukwelashwa. Leyo ndlela iphephe kakhulu kunezinye eziningi zokwelapha ezijovwayo, ngokweqiniso.

2. Ubani okufanele agweme ukwelashwa kwe-PDN

Ngisho nezinzuzo ezinhle ze-PDRN, akuyona eyawo wonke umuntu. Kufanele ugweme ukwelashwa kwe-PDRN uma: - Ukhulelwe noma uncelisa (asinayo idatha eyanele yokuphepha lapha, ngakho-ke iphephe kangcono kunokuzisola) - Uba nokungezwani komzimba ne-salmon noma yiziphi izingxenye zomjovo - Unokutheleleka okusebenzayo endaweni yokwelashwa - Unohlelo lokuzivikela komzimba osengozini noma usebenzisa imithi yokuvimbela i-immunosuppressant

Uma unanoma yiziphi izimo zempilo ezingalapheki, hlala ukhuluma nomhlinzeki wakho wokunakekela oyinhloko ngaphambi kokuthola noma yikuphi ukwelashwa okusha okujovwayo, kuhlanganisa ne-PDRN.

Imibuzo Evame Ukubuzwa Mayelana ne-PDRN

Ihlala isikhathi esingakanani imiphumela yokwelashwa kwe-PDN?

Izinzuzo ze-PDRN ezesikhathi eside, hhayi okwesikhashana njengama-hyaluronic acid fillers, afaka nje ivolumu encibilika ngokuhamba kwesikhathi. Ezigulini eziningi, imiphumela egcwele evela ochungechungeni lwemithi engu-3 ye-PDRN ihlala izinyanga eziyi-12-18. Ungathola ukwelashwa kwesondlo okukodwa njalo ezinyangeni eziyisi-6-12 ngemva kwalokho ukuze ugcine izinzuzo ziqhubeka. Lokho kungenye yezinzuzo ezinkulu ze-PDRN - wakha intuthuko yesikhathi eside, hhayi nje ukuthola ukulungiswa kwesikhashana.

Zingaki izindlela zokwelapha ze-PDRN engizidingayo?

Abantu abaningi badinga uchungechunge lwemithi ye-PDRN engu-3 ehlukaniswe ngamaviki angu-2-4 ukuze bathole izinzuzo ezigcwele ze-PDN. Yilokho okusetshenziswa zonke izifundo ezinkulu, futhi yilokho engikubone kusebenza kangcono ezigulini zami. Uma wenza nje ukwelashwa kwesondlo ngemva kochungechunge lwakho lokuqala, udinga eyodwa kuphela ngemva kwezinyanga eziyisi-6-12. Ngokulimala kwe-musculoskeletal, abantu abaningi babona imiphumela egcwele ngemva kokujova okungu-1-2, kuye ngobunzima bomonakalo.

Ingabe i-PDRN iyafana ne-PRP?

Cha, azifani, nakuba zombili kuyizindlela zokwelapha ezivuselelayo ezikhuthaza ukuzilungisa komzimba wakho. I-PRP (i-plasma ecebile nge-platelet) isebenzisa amangqamuzana akho egazi agxile nezici zokukhula, kuyilapho i-PDRN iyinhlanganisela etholakala ku-salmon ehlanzekile ebesikhuluma ngayo. Izinzuzo ze-PDRN empeleni zihambisana kakhulu kune-PRP ezimweni eziningi, ngoba i-PDRN ine-concentration standardized njalo, kuyilapho i-PRP ingahluka ngokusekelwe ekubaleni kwakho kwamangqamuzana egazi. Abahlinzeki abaningi empeleni bayawahlanganisa ukuze bathole imiphumela engcono kakhulu, kodwa awayona into efanayo.

Isiphetho: Ingabe I-PDRN Ikulungele?

Ake sikuphethe lokhu. Izinzuzo ze-PDRN zihlaba umxhwele ngempela uma isetshenziselwa abantu abalungile, futhi ucwaningo lusekela lokho engikubone emtholampilo wami eminyakeni emi-3 edlule.

Uma ufuna indlela engeyona yokuhlinzwa yokuthuthukisa i-collagen yakho, ukuthuthukisa ukuthungwa kwesikhumba sakho, ukunciphisa ububomvu, noma ukusheshisa ukulimala kwezicubu ezithambile ezinenkani, i-PDRN cishe kufanelekile ukukhuluma nomhlinzeki oqeqeshiwe mayelana.Imiphumela emibi imnene, isikhathi sokuphumula sincane, futhi imiphumela iyisikhathi eside, okuwukuwina encwadini yami.

ngokweqiniso, nganginokungabaza ekuqaleni emuva ngo-2021, kodwa ngemva kokubona imiphumela neziguli zami nokuthola izinzuzo ze-PDRN ngokwami, ngingumuntu oguqukayo.Vele uqiniseke ukuthi uya kumhlinzeki oqeqeshiwe, onolwazi, futhi ungesabi ukubabuza mayelana nolwazi lwabo nge-PDRN ngaphambi kokubhuka. Leyo yindlela engcono kakhulu yokuqinisekisa ukuthi uthola izinzuzo ezigcwele ze-PDRN ngokuphepha.

Kulungile? Akuwona wonke umuntu, kodwa kumuntu olungile, kuwushintsho oluphelele lomdlalo.