Caafimaadka 45S5 Biyoactive Glass
Medical 45S5 Bioactive Glass waa walxo noole firfircoon oo caafimaad ahaan la xaqiijiyay oo caan ku ah dib u soo noolaynta lafaha aad u wanaagsan, lafo-conductivity, iyo noole laqabsiga. Waxay kicisaa samaynta hydroxyapatite waxaana si weyn loogu isticmaalaa hagaajinta lafaha, ilkaha, iyo codsiyada caafimaadka.
Sharaxaada
calaamade
Caafimaadka 45S5 Sharaxaada Alaabta Bioactive
Muraayada bioactive waa nooc cusub oo biomaterial ah oo loo isticmaalo dib-u-soo-noolaynta unugyada, haysashada firfircoonida noolaha, waafaqsanaanta unugyada jilicsan iyo kuwa adag labadaba, iyo heerarka hoos u dhaca la xakameyn karo.
Muraayada ugu badan ee matale ee loo isticmaalo kiliinikada lafaha, iliga, iyo hagaajinta dhaawaca maqaarka waa 45S5, kaas oo iska leh Na2O-CaO-SiO2-P2O5 nidaamka quaternary.
Qalabkan cusub ee caafimaadka ayaa soo bandhigaya biocompatibility aad u fiican, jawi jireed, wuxuu dhalin karaa lakabka macdanta hydroxycarbonate apatite ee lafaha kor u qaadaya iyada oo loo marayo macdanta dusheeda, taas oo lagu gaaro isku xidhka kiimikada ee u dhexeeya walxaha iyo unugyada martida loo yahay.
Caafimaadka 45S5 Tilmaamaha Alaabta Bioactive
| Nooca Alaabta Caafimaadka | Qaabka | Tilmaamaha Codsiga | Tilmaamid | Waqtiga Hogaaminta | Macluumaadka Patent | Xidhmada Dukumentiyada Farsamada |
| Buuxinta cilladda lafaha qayb weyn, dhisidda xuubka lafaha, qaabka osteoconductive ee qolofyada lafaha dalool | >200μm | Nooca taageerada muddada-dheer | 100g/500g/1kg | 14 maalmood | CN202610037550.3 | Qalab Caafimaad Master File Diiwaangelinta Maamulka Alaabta Caafimaadka Qaranka (loo gudbiyay ogolaansho) + COA (Shiine/Ingiriis) + MSDS (Shiine/Ingiriis) |
| Buuxinta ciladaha waaweyn ee lafaha, agabka beddelka lafaha, hagaajinta lafaha dhegta dhexe | <200μm | Nooca hagaajinta lafaha-qaabaynta sare | 100g/500g/1kg | 14 maalmood | CN202610037550.3 | Qalab Caafimaad Master File Diiwaangelinta Maamulka Alaabta Caafimaadka Qaranka (loo gudbiyay ogolaansho) + COA (Shiine/Ingiriis) + MSDS (Shiine/Ingiriis) |
| Buuxinta ciladaha lafaha yaryar iyo kuwa dhexdhexaadka ah ee aan joogtada ahayn, dhaymo hagaajinta dhaawaca, xoqida daawada cadayga | <120μm | Nooca osteogenesis-ka degdega ah | 100g/500g/1kg | 14 maalmood | CN202610037550.3 | Qalab Caafimaad Master File Diiwaangelinta Maamulka Alaabta Caafimaadka Qaranka (loo gudbiyay ogolaansho) + COA (Shiine/Ingiriis) + MSDS (Shiine/Ingiriis) |
| Buuxinta cilladaha lafaha yaryar iyo kuwa dhexdhexaadka ah ee aan joogtada ahayn, dhaymada hagaajinta dhaawaca, isbogsiinta is-bogsiinta lafaha | <45μm | Nooca dayactirka ugu yar ee firfircoon ee firfircoon | 100g/500g/1kg | 14 maalmood | CN202610037550.3 | Qalab Caafimaad Master File Diiwaangelinta Maamulka Alaabta Caafimaadka Qaranka (loo gudbiyay ogolaansho) + COA (Shiine/Ingiriis) + MSDS (Shiine/Ingiriis) |
| Hemostasis iyo dib u soo kabashada xididdada dhiigga, dhaymada nabarrada iyo bogsashada, dareen-celinta daawada cadayga iyo dib u soo celinta | <30μm | Nooca bogsashada iyo hagaajinta macdanta | 100g/500g/1kg | 14 maalmood | CN202610037550.3 | Qalab Caafimaad Master File Diiwaangelinta Maamulka Alaabta Caafimaadka Qaranka (loo gudbiyay ogolaansho) + COA (Shiine/Ingiriis) + MSDS (Shiine/Ingiriis) |
Doorka Waxqabadka ee 45S5 Bioactive Glass
I. Kor u qaadida isku xidhka lafaha
Oogada maqaar-galaha waxay si toos ah u samayn kartaa xidhidhyo kiimiko oo xooggan oo leh unugyo lafo ah.
Tani maaha kaliya ku dheggan jirka, laakiin samaynta lakabka hydroxyapatite (HCA) oo la mid ah lafta dabiiciga ah
II.Kor u qaadista lafo-jileecu iyo dib u soo kabashada lafaha
● Siideynta ions sida Ca²⁺, SiO₄⁴⁻, PO₄³⁻, iyo Na⁺
●Kicinta lafo-beelka:
o Kordhinta unugyada unugyada
o Kor u qaadida muujinta hidda-wadaha la xidhiidha osteogenesis
o Lafo cusub oo la dedejiyey
III. Samaynta lakabka Hydroxycarbonate Apatite (HCA).
Habka falcelinta caadiga ah ee soo socota waxay ku dhacdaa dareeraha jidhka:
1.Na⁺ waxay ku beddeshaa H⁺, abuurista jawi alkaline ah.
2.Shabakadda Si-O-Si way burburtaa, iyada oo samaysa Si-OH.
3.Ca²⁺ iyo PO₄³⁻ waxay ku ururaan dusha sare.
4.Lakabka HCA ayaa la sameeyay (la mid ah macdanta lafaha dabiiciga ah).
IV.Bakteeriyada iyo ka hortagga caabuqa
●Ion sii dayntu waxay kordhisaa pH-ga deegaanka iyo cadaadiska osmotic.
●Waxay joojisaa koritaanka bakteeriyada kala duwan.
●Waxay yarayn kartaa halista caabuqa qalliinka kadib.
V.Dhibaatooyinka iyo Beddelka Nudaha La Xakameeyay
●Waxyaabaha ay si tartiib tartiib ah u hoos ugu dhacaan jirka.
Isla mar ahaantaana, waxaa lagu beddelaa unug cusub oo lafo ah.
●Heerka xaalufka waxaa lagu xakameyn karaa saamiga ka kooban iyo cabbirka walxaha.
45S5 Qaabka Isticmaalka Dhalooyinka Bioactive
1.Dib-u-habaynta Lafaha / Lafaha: Si toos ah loogu dhejiyo granules ama budada cilladda; ama loo isticmaalo in lagu abuuro qolof lafaha.
2.Dentistry: budada lagu daray daawada cadayga, balastarka ilkaha, iyo qalabka buuxinta periodontal.
3.Dayactir nabarka / Injineeriyada Unug Jilicsan: Isku-darka hydrogels, dhaymada, ama xuubabka, oo ah qaab yar/nanoparticle.
4.Cosmetics / Anti-gabowga Dayactirka (marxaladda R&D): budo-yar oo lagu daray maaskaro wejiga ama walxaha qurxinta.
5.Antibacterial Materials: Waxaa lagu daray hydrogels, dhaymo, ama dahaarka.
nala soo xidhiidh
Alaabooyinka caanka ah ee la xidhiidha
Hyaluronic acid tayo sare leh
Hyaluronic acid (sodium hyaluronate) oo nadiif ah oo nadiif ah oo budo ah oo loogu talagalay qaababka qurxinta iyo daryeelka maqaarka. Waxay siisaa haynta qoyaanka oo heer sare ah, waxay wanaajisaa fuuq-baxa maqaarka, waxayna kordhisaa waxqabadka alaabta. Ku habboon serums, kiriimyada, waji-xidhka, iyo alaabta daryeelka maqaarka ee xirfadleyda ah. Baakadaha badan iyo baakadaha OEM ayaa diyaar u ah soosaarayaasha caalamiga ah.
Isticmaalka maalinlaha ah ee 45S5 Bioactive Glass
45S5 Bioactive Glass waa walxo noole firfircoon oo caafimaad ahaan la xaqiijiyay oo caan ku ah dib-u-soo-noolaynta lafaha, osteoconductivity, iyo noole ku habboonaanta. Waxay kicisaa samaynta hydroxyapatite waxaana si weyn loogu isticmaalaa hagaajinta lafaha, ilkaha, iyo codsiyada caafimaadka.
Serum timaha timaha
Serum Kobaca timaha timaha ayaa leh PDRN iyo peptides koritaanka timaha ee lala beegsaday si ay u taageeraan dheelitirka madaxa iyo firfircoonida timaha. Waxay ka caawisaa nasinta iyo nafaqaynta madaxa, wanaajisaa deegaanka madaxa, waxay xoojisaa xannibaadda madaxa, waxayna taageertaa timo caafimaad leh, oo dhumuc weyn leh. Caanaha ugu yar, ee bilaashka ah ee wax lagu daro kuma jiraan hormoono, wax ilaaliya, ama maaddooyin qallafsan, taasoo ka dhigaysa mid dabacsan oo ku habboon maqaarka maqaarka xasaasiga ah.
(SOD-1W) Daawada Superoxide Dismutase
Recombinant Human Superoxide Dismutase oo leh firfircoonida enzyme ≥10000 U/mg, daahirsanaanta ≥95%, qaabdhismeedka dimer deggan iyo miisaanka kelli ee 32 kDa.
Polydeoxyribonucleotide
PDRN (polydeoxynucleotide) waa jajab DNA ah oo laga soo saaro unugyada salmon. Waxay la wadaagtaa qiyaastii 98% homology-ga DNA-da aadanaha. PDRN iskeed isu soo saartay waxay leedahay miisaan kelli ah ≤100 bp waxayna bixisaa saldhigyada aashitada nucleic inta lagu jiro dheef-shiid kiimikaadka gacanta.
Isku-darka Collagen Gel
Alaabtani waxay isticmaashaa 100% heerka-caafimaadka recombinant nooca III kolajka, soo bandhigaya bioocompatibility aad u fiican oo aan khatar u ah diidmo difaaca. Marka la isticmaalo iyadoo lala kaashanayo hyaluronic acid, waxay taageertaa fuuq-baxa xuubka iyo ilaalinta xannibaadaha. Marka ay gaadho 37°C, waxa ay samaysaa filim ilaalin ah oo la neefsan karo iyada oo aanay jirin wax dareen ah oo jidh shisheeye ah. Waxa aanay ku jirin maaddooyin xayawaanno ka soo jeeda, hormoonno, aalkolo, ama walxaha kiimikaad ee isku xidha, taas oo ka dhigaysa mid ku habboon daryeelka maalinlaha ah iyo soo kabashada.
(SOD-bio-5k) Daawada Superoxide Dismutase
Recombinant Human Superoxide Dismutase oo leh firfircoonida enzyme ≥10000 U/mg, daahirsanaanta ≥95%, qaabdhismeedka dimer deggan iyo miisaanka kelli ee 32 kDa.
Dharka dareeraha ah
Isku darka kolajka ee heerka-caafimaadka iyo hyaluronic acid oo loogu talagalay hagaajinta unugyada horumarsan iyo dib u soo kabashada maqaarka. Waxay xoojisaa fuuq-baxa, taageertaa bogsashada nabarrada, waxayna wanaajisaa barti maqaarka. Ku habboon codsiyada caafimaadka, bilicda, iyo cilmiga noolaha.
Rose PDRN
PDRN (polydeoxynucleotide) waa jajab DNA ah oo laga soo saaro unugyada salmon. Waxay la wadaagtaa qiyaastii 98% homology-ga DNA-da aadanaha. PDRN iskeed isu soo saartay waxay leedahay miisaan kelli ah ≤100 bp waxayna bixisaa saldhigyada aashitada nucleic inta lagu jiro dheef-shiid kiimikaadka gacanta.
(Nooca DK) Microsphere Caafimaad Hydroxyapatite
Dareen-celiyeyaasha ilkaha, qalabka hemostatic, alaabta dhaymada nabarrada waxay saameyn degdeg ah ku yeelataa duritaanka maqaarka hoostiisa ee degdegga ah ee wax-yeeleeya bilicda caafimaadka (murbad hoose oo qoto dheer iyo duritaan supraperiosteal)
(SOD-bio-2k) Daawada Superoxide Dismutase
Recombinant Human Superoxide Dismutase oo leh firfircoonida enzyme ≥10000 U/mg, daahirsanaanta ≥95%, qaabdhismeedka dimer deggan iyo miisaanka kelli ee 32 kDa.
Isticmaalka maalinlaha ah Recombinant Human Superoxide Dismutase
Recombinant Human Superoxide Dismutase oo leh firfircoonida enzyme ≥10000 U/mg, daahirsanaanta ≥95%, qaabdhismeedka dimer deggan iyo miisaanka kelli ee 32 kDa.
(Nooca SDK) Microsphere Hydroxyapatite
Daahan bioactive ee sagxadaha maqaar-galaha, agabka dayactirka lafaha duritaan dusha sare ee jirka oo dheer oo raaga
(Nooca HD) Microsphere Medical Hydroxyapatite
Daawooyinka maxaliga ah/walaxda firfircoon ee sidayaasha sii daynta joogtada ah, dahaarka daawadu ku raran tahay Sidayaal-soo-dejin joogto ah oo lagu hagayo microspheres dib u soo kicinta lafaha ee firfircoon, buuxinta is dhexgalka unug isku dheeli tiran ee bilicda caafimaadka, microspheres hemostatic
Maaskaro Waji Oo Soo Dhaweeya
Maaskaradan xaashida nasteexada leh waxay ka kooban tahay sodium hyaluronate, panthenol, hydroxyapatite, iyo soosaarayaal botanical khamiir leh si ay uga caawiso fuuq-baxa, xasilinta, iyo taageeridda xannibaadda maqaarka. Loogu talagalay maqaarka xasaasiga ah, waxay bixisaa daryeel raaxo leh oo leh xaashi microfiber jilicsan, maqaarka u-saaxiibtiran.
Labeen dib loo hagaajiyay
Kareemkan wejiga waxaa lagu sameeyay PDRN-ka salmon, oo lagu daray SOD, niacinamide, squalane, pro-xylane, panthenol, iyo peptides. Waxay ka caawisaa ilaalinta fuuq-baxa maqaarka, raaxada, iyo muuqaal caafimaad leh iyadoo taageereysa xannibaadda dabiiciga ah ee maqaarka. Miisaanka fudud ayaa si fudud u nuugaya iyada oo aan dufan lahayn, taas oo ka dhigaysa mid ku habboon isticmaalka maalinlaha ah. Ka madax banaan khamriga, hormoonnada, iyo biraha culus, waxaa loogu talagalay daryeelka maqaarka joogtada ah waxaana sidoo kale loo mari karaa maaskaro ahaan nafaqo dheeraad ah.
Fadlan fariin noogu dhaaf